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Homocysteine


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Ray Sahelian, M.D.

Homocysteine is a derivative of the amino acid methionine. It received a great deal of media attention in 1997 following publication of articles in medical journals indicating that a high blood level of homocysteine is a potential risk factor for atherosclerosis and heart disease. Kilmer McCully, M.D., a pathologist at the Veterans Affairs Medical Center in Providence, Rhode Island, had been claiming for at least two decades that homocysteine is as important a risk factor for heart disease as cholesterol, but few in the medical profession paid serious attention to his claim. Dr. McCully was vindicated with the publication of additional scientific articles in the 1990s, most of which confirmed the dangers of elevated homocysteine levels. Fortunately, homocysteine levels can be easily lowered by taking supplements of B vitamins, particularly folic acid, B6, and B12 (methylcobalamin).

High Homocysteine Levels: Danger to the Brain?

In addition to contributing to cardiovascular conditions, homocysteine may also be detrimental to the brain since it can act as a toxin to brain cells. Dr. L. Parnetti and colleagues, from Perugia University in Italy published in article discussing the role of homocysteine in cognitive decline. They say, "Homocysteine may represent a metabolic link in the cause of atherosclerotic vascular diseases and old-age dementias. Excessive homocysteine is an independent risk factor for coronary artery disease, peripheral vascular disease, and cerebrovascular disease. Homocysteine is a reliable marker of vitamin B12 deficiency, a common condition in the elderly, which is known to induce neurological deficits including cognitive impairment. A high prevalence of folate deficiency has been reported in geriatric patients suffering from depression and dementia. Both these vitamins occupy a key position in the remethylation and synthesis of S-adenosylmethionine (SAM-e), a major methyl donor in the central nervous system. Therefore, deficiencies in either of these vitamins leads to a decrease in SAM-e and an increase in homocysteine, which can be critical in the aging brain."

        Nutritionists at Tufts University in Boston have also found a connection between B vitamins, homocysteine, and memory. They investigated the relations between blood concentrations of homocysteine and vitamins B-12, B-6 and folate, and scores from a battery of cognitive tests for seventy male subjects, aged 54-81 years. Lower concentrations of vitamin B-12 and folate and higher concentrations of homocysteine were associated with poorer memory. Furthermore, people with low levels of vitamin B12 or folic acid may have a higher risk of developing Alzheimer's disease

How to reduce high Homocysteine levels

Adequate intake of folic acid, B6, and B12 will assure that homocysteine levels are kept under control. Considering the possibility that there may be individuals, especially the elderly, who are deficient in B6, folic acid, and B12, an inexpensive and simple way to decrease the rate of damage to the brain from homocysteine would be by supplementing with these vitamins.

Cellfood DNA/RNA has been shown to lower Homocysteine Levels!

Dietary supplements are not to be used to prevent or treat any disease. The Statements on this web page have not been evaluated by the FDA. Any information provided on this website is not a substitute for the advice of a licensed medical practitioner. Individuals are advised not to self-medicate in the presence of significant illness. Ingredients in supplements are not drugs and may not be foods.
CELLFOOD DNA/RNA is marketed internationally by J. Wood & Associates.  To order CELLFOOD DNA/RNA for your store please call 405-285-7052 or email us at info@myfreenewsletter.com








 

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