Longevity Enhancing Cofactors

To make CELLFOOD DNA/RNA an ultimate anti-aging formula, it also provides clinically tested nutrients that can reverse the aging clock at the DNA level. These nutrients have also been shown to protect and repair DNA and prevent DNA mutations, thus reducing the risk of cancer and preserving cells at a more youthful level.

Perhaps the primary mechanism of aging in the cells is the loss of DNA markers called methyl groups (a simple group with one carbon and three hydrogen atoms, known as CH3). At birth, DNA in the cell nucleus has a significant fraction of its cytosine residues tagged with methyl groups. Depending on the cell type, the level of cytosine methylation ranges from 2-6%.

Aging is regulated and programmed by the gradual loss of methyl groups from nuclear DNA. When 40% of the methyl groups are lost, degenerative death typically occurs.

All of the factors known to cause aging accelerate the loss of methyl groups from DNA. For example, smoking, poor nutrition, poor vitamin intake, low exercise, environmental toxin absorption, and radiation exposure all accelerate methyl group loss.

Any intervention that slows, stops, and reverses the loss of methyl groups from DNA is slowing, stopping, and even reversing aging at the DNA level. CELLFOOD DNA/RNA provides the most powerful laser enhanced nutrient factors for improving DNA methylation ever studied.

The most sensitive blood chemistry test for determining the rate of methyl group loss from DNA is called homocysteine. The higher the homocysteine level above 4-6, the greater the rate of methyl group loss from DNA. The teenage level of homocysteine is 4-6, which tends to rise 1-2 points per decade, such that at 60-70, the level is typically 12-15 or higher. Elevated homocysteine has in parallel with aging effects also been found to be a cardiac risk factor. Above a level of 6.3, cardiac risk rises exponentially, with a level of 15 carrying a risk four times, and a level of 20 carrying a risk that is nine times greater for a major cardiovascular incident than that of the general population.

In a major double blind randomized placebo controlled clinical study the effects of laser-enhanced nutrients on homocysteine reduction and other important metabolic factors and clinical symptoms. This study was reviewed and approved by the Western Institutional Review Board as meeting the international standards for the design and safety of human clinical research.

Perhaps the single most powerful homocysteine-lowering nutrient is trimethylglycine, or TMG. This molecule has three methyl groups to donate, hence the prefix trimethyl. It is also known as betaine because it is a natural substance derived from sugar beets.

Previous research has shown that high dose betaine can reduce the risk of mortality the first year after a heart attack from 25% to 0%. In addition, high dose betaine in conjunction with vitamin cofactors has been the only intervention that has permitted women with a genetic disease of high homocysteine levels (homocystinuria) to conceive and have normal gestations and deliveries. In other persons with homocystinuria, adding betaine has reversed neurologic defects and caused gray hair to darken and lost hair to regrow.

Laser treatment of a betaine compound has shown dramatic molecular effects that favor greater biological activity. Crystals grown using Dr. Ovokaitys' system show a very high level of homogeneity compared to the irregularities and numerous defects seen in control crystals grown without the laser. Homogeneity reduces the energy required by enzymes to make the desired products.

X-ray crystallography, the gold standard for determining explicit molecular shape since 1915, also showed striking findings. The laser treated betaine compound had a uniform flattened and stretched shape not matched by the control untreated molecules. The flat stretched shape has higher electric and magnetic field moments that also promote more efficient enzymatic action.

The study formula for boosting methyl group transfers and reducing homocysteine contained laser treated betaine as the main component. In addition laser treated vitamin cofactors that are known to support these pathways were also included, particularly vitamins B6, B12, and folic acid. Niacin was also included to assist with fat metabolism in addition to homocysteine reduction, for further cardiovascular support.

The treatment group received increasing doses of the laser enhanced methylation formula over a 3-month period of time, whereas the placebo group only received sugar pills. Subjects had blood drawn at baseline and every month for homocysteine levels, blood counts, and other metabolic tests. Subjects completed daily written reports and each week completed an extensive standardized symptom survey.

By the completion of the study, the treatment group showed very dramatic metabolic improvements not seen in the placebo group. Homocysteine levels for the treatment group started at values that on average carry about double the cardiac risk that by the end of the study reduced to values at less than the risk of the general population. The reduction at every dosage level was highly statistically significant, the homocysteine reduction for the group suggestive of a 20-30 year physiologic reduction in this aging measure.